5 SIMPLE STATEMENTS ABOUT PKRRATING EXPLAINED

The activated enzyme then phosphorylates its big substrate, the translational initiation factor eIF2α. The ensuing translational arrest blocks viral replication. PKR belongs to your conserved family members of 4 protein kinases (PKR, PERK, GCN2, HRI) that all phosphorylate eIF2α in reaction to various stimuli12, triggering the built-in worry resp